Cerium Ammonium Nitrate
CAS NO: 16774-21-3 EINECS: 240-827-6
Molecular Formula: Ce(NH4)2(NO3)6
Molecular Weight: 548,22
Properties：Orange red crystal, soluble in water, ethanol and inorganic acid, easy to deliquescence in the air.
Synonyms：Cerium ammonium nitrate; cerium ammonium nitrate double salt; can.
| CODE | CAN-4N/A177 | CAN-3N5/A178 | CAN-3N/A179 |
|---|---|---|---|
| TREO>% | 30.5 | 30.5 | 30 |
| CeO2/REO>% | 99.999 | 99.95 | 99.9 |
| Ce(NH4)2(NO3)6>% | 98.5 | 98 | 97 |
| Non-rare earth impurities＜μg/g | |||
| Fe | 0.5 | 1 | 3 |
| Ca | 0.5 | 1 | 3 |
| Na | 0.5 | 1 | 3 |
| K | 0.5 | 1 | 1 |
| Pb | 0.5 | 1 | 1 |
| Cu | 0.5 | 1 | 1 |
| Ni | 0.5 | 1 | 1 |
| NTU | 0.8 | 1 | 1.5 |
Applications in organic chemistry
In organic synthesis, CAN is useful as an oxidant for many functional groups (alcohols, phenols, and ethers) as well as C–H bonds, especially those that are benzylic. Alkenes undergo dinitroxylation, although the outcome is solvent-dependent. Quinones are produced from catechols and hydroquinones and even nitroalkanes are oxidized.
For the synthesis of heterocycles in Pharma industry
Catalytic amounts of aqueous CAN allow the efficient synthesis of quinoxaline derivatives. Quinoxalines are known for their applications as dyes, organic semiconductors, and DNA cleaving agents. These derivatives are also components in antibiotics such as echinomycin and actinomycin. The CAN-catalyzed three-component reaction between anilines and alkyl vinyl ethers provides an efficient entry into 2-methyl-1,2,3,4-tetrahydroquinolines and the corresponding quinolines obtained by their aromatization.
As a deprotection reagent
CAN is traditionally used to release organic ligands from metal carbonyls. In the process, the metal is oxidised, CO is evolved, and the organic ligand is released for further manipulation.
CAN is used to convert para-methoxybenzyl and 3,4-dimethoxybenzyl ethers, which are protecting groups for alcohols. Two equivalents of CAN are required for each equivalent of para-methoxybenzyl ether. The alcohol is released, and the para-methoxybenzyl ether converts to para-methoxybenzaldehyde.
Other applications
CAN is also a component of chrome etchant, a material that is used in the production of photomasks and liquid crystal displays. Cerium (IV) ammonium nitrate ((NH4)2Ce(NO3)6) is a one-electron oxidizing agent that is used for oxidative addition reactions of electrophilic radicals to alkenes, enabling intermolecular and intramolecular carbon-carbon and carbon-heteroatom bond formation. CAN also oxidizes secondary alcohols into ketones and benzylic alcohols into aldehydes. Cerium Ammonium Nitrate used for chemical reagent and ternary catalyst. It is a specialised oxidizing agent in organic synthesis and a standard oxidant in quantitative analysis.
Packing: Drum inner with plastic bag. Net weight 25/50 kg.
Storage: Store In Cool, Dry Place In Tightly Closed Containers. Incompatible With Oxidizing Agents.
